Serotypical study of dengue virus and clinical characteristics in patients with febrile sharp disease
DOI:
https://doi.org/10.51252/rsayb.v2i1.518Keywords:
arthralgia, eye pain, hemorrhagic fever, myalgiasAbstract
The objective of this study was to determine the frequency of Dengue virus (DENV) serotypes and describe its clinical presentation in patients with acute febrile illness, January-June 2020, Peru. From a total of serum samples from health centers, the presence of DENV was studied using RT-PCR, NS1 antigen and IgM antibodies. A standardized questionnaire was used to collect information on clinical symptoms. Within the evaluation of 496 patients with acute febrile illness (AFI) and suspected dengue were studied, consecutively between the months of January to June. Within the symptoms evaluated, 495 (99%) patients between women and men presented fever, and only 1 person did the opposite. The following symptoms were evaluated according to the incidence of cases: arthralgia present in 372 (75%) people; myalgia in 340 (68.5%), headaches in 341 (68.8%), eye pain in 321 (64.7%), low back pain in 303 (61.1%), extreme rash in 189 (38.1%) %) presenting incidence in adolescents, conjunctivitis symptoms in 92 (18.5%) and nausea in 185 (37.3%). The Dengue diagnosis demonstrated that the NS1 and the IgM anti-DENV have valid sensitivity and specificity.
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